The risks and disadvantages of consanguineous marriage on individuals, the family and society
an introduction :
Consanguineous marriage is a marriage between people of the same origin. Consanguinity can be descended from the mother or it can be descended from the father. No less important, inbreeding is generally examined of two degrees; Marriages that take place between spouses whose parents are siblings are called inbreeding of the first degree (inbreeding).
We must also discuss the effects of consanguineous marriage on the family and society.
Consanguineous marriage is a serious medical problem in our society, as is the case in many other countries. Because of the negative effects of genetic diseases on their frequency, they must be emphasized and discussed.
What are the risks that consanguineous marriage leads to?
It was reported that the frequency of stillbirths in inbreeding increased almost twice compared to the normal society (1.24% in the normal society, 2.14% in inbreeding) when it is examined when abortion and stillbirth are taken together, the same increase is also surprising (5.21% in the normal society) , 10.55% in cases of consanguineous marriage).
In terms of birth losses, there is an increase of 50% (10.76% in normal society, 16.29% in consanguineous marriages).
Reports also indicate that birth defects increase 10 times in consanguineous marriages
Consanguineous marriage increases the incidence of recessive and multifactorial genetic diseases. Genes are structures that enable traits to be passed on from parents to offspring.
The probability of similarities between genes in the same family is very high, because they are passed on from parents to offspring. In diseases where the risk of consanguineous marriage increases, both spouses must have the same type of defective gene. Due to the increased frequency of genetic similarities between relatives, the probability of having a sick child among relatives increases
Matching the mother’s and father’s blood groups does not indicate that there is no risk. The risks associated with blood incompatibility and inbreeding are absolutely not relevant
It is also not recommended for persons with disabilities (such as low vision or hearing) to marry the same disability. If people with the same disability marry, the risk is greater for the child.
Can consanguineous marriage give birth to a healthy child?
It may be possible, but the risk of having a sick child increases in those who have inbreeding compared to other marriages. The most important point that misleads the family is that healthy children are born from inbreeding by others in their family and environment. Having healthy children from previous pregnancies does not show that there is no risk in future pregnancies, and the presence of sick children does not show that they will not have healthy children.
In these couples, the risk of having a sick child increases, but approximately 95% of the children born are healthy. There may be healthy and sick children from the same parents.
How should the close spouses be monitored?
You must draw a family tree consisting of 3 generations and obtain information about each individual. If symptoms of any disease are detected in the family tree, information about this situation must be obtained.
Medical records, photos and information provided by the family should be evaluated and if necessary, experts in the relevant branch should be consulted. According to the inheritance pattern of the disease.
The risk is calculated for the individual we investigated.
If there is an increased risk, tests for this disease are planned according to the results of the test, if there is a risk in the family pregnancy.
Diagnosis should be planned before birth
if there is no specific risk factor in the family. The transmission of recessive diseases common in that population is tested. This is done in terms of thalassemia in our country.
How follows pregnancy in inbreeding?
Should be evaluated, USG should follow these families during pregnancy. and biochemical screening test during pregnancy, follow-up the second step of their children at birth and investigate hearing loss or metabolic diseases.
Double, triple and quadruple tests are performed in normal pregnancies, and detailed ultrasound tests are performed in these pregnancies. Double, triple and quadruple tests do not show genetic diseases through consanguineous marriage.
But it is performed to check for chromosomal abnormalities, as in normal pregnancies, in a marriage that takes place between 11-14 weeks at (CVS) relatives, some diseases can be detected using chorionic villus sampling. In this case, the family may request that the pregnancy be terminated.
Therefore, we must publish what are the effects of consanguineous marriage on the family and society to avoid it and build a healthy society.
The risks and psychological and social harms of consanguineous marriage and its negative impact on individuals, the family and society, and the mechanism for preventing such harms.
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